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Published: August 06, 2008 08:00 pm    print this story  

Lauran Neergaard: Potential fix for lazy eye

By LAURAN NEERGAARD
AP Columnist

Dr. Paul Dougherty delicately slipped a tiny lens inside the right eye of 7-year-old Megan Garvin -- a last-ditch shot at saving her sight in that eye.

The California girl recently became one of a small number of U.S. children to try an experimental surgery to prevent virtual blindness from lazy eye diagnosed too late, or too severe, for standard treatment.

The new approach: Implantable lenses, the same kind that nearsighted adults can have inserted for crisper vision -- but that aren't officially approved for use in children.

Up to 5 percent of children have amblyopia, commonly called lazy eye, where one eye is so much stronger than the other that the brain learns to ignore the weaker eye. Untreated, the proper neural connections for vision don't form, eventually rendering that eye useless.

Catch it early -- preferably by preschool -- and it can be fairly easy to fix by patching over the strong eye, or using special drops in it, for several hours a day so that the brain is forced to use the weak eye. But the older the child is, the less effective the treatment -- and by age 9, brain-eye connections are pretty well set.

The leading cause is eyes that aren't in perfect alignment. But a big difference in focusing power also triggers amblyopia. That's what happened with the Garvin girl, who had near-perfect vision in one eye but the other was too nearsighted to even see the big E on the eye chart.

Glasses weren't doable: One side would have required a clear lens and the other a Coke-bottle thickness, a prescription of minus 12 diopters. Contacts and young kids are a tough match. Megan cried when her mother inserted it. Teachers would call to say it had popped out.

Frustrated, the Garvins ultimately opted for the implant. That's just the first step. Months of patching lie ahead to try to reverse the lazy eye, or the brain would just stick with the connections it has already formed to her strong eye. Dougherty gave no guarantees.

Implantable lenses for adults, called phakic intraocular lenses or IOLs, hit the U.S. market in 2004. Unlike cataract surgery that requires removal of the eye's natural lens because it is clouded, these lenses are put on top of a natural lens that can't focus properly, thus helping sharpen vision.

They have some risks: Surgical infection, inflammation, a potential for cataracts to form. At about $4,000 an eye, it's more expensive than the controversial laser eye surgery LASIK, but the lenses can be removed if there are problems.

Other surgeons are experimenting with LASIK in children like Megan, although she wasn't a LASIK candidate -- her corneas were too thin for it to be done safely, and Dougherty says it doesn't work well for such severe nearsightedness.

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Photos


Lauran Neergaard / (Click for larger image)



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